Without
ないで
Means “without doing”. Formed with a verb in the negative tense (ない). It is a bit more casual than ずに.
Example
勉強しないで卒業した。 I graduated without studying.
ずに
Means “without doing”. Formed with a verb in the negative tense (ない) by removing the -ない stem and adding ずに. する transforms to せずに. It is a bit more formal than ないで.
Example
毎日食べずに出かける。 Everyday, I go out without eating.